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The researchers included the costs of medication, other medical therapy, and worker productivity in their analysis

Many authors discuss the inadequacy of guidelines when written based on general consensus and expert opinion, rather than on high-level clinical evidence, noting that case reports, retro/prospective studies, and observational studies, as is mostly what is currently available, are often insufficient to inform clinical practice (Australian Diabetes Society, National Association of Clinical Obesity Services, Gastroenterological Society of Australia, and Australian and New Zealand College of Anaesthetists n.d.)

Signal intensities were normalised to DSS

It is not considered to be a carcinogen, and no data are available regarding teratogenic or reproductive effects